It remains unknown how changes to the endocannabinoid system could lead to the marijuana addiction development of CHS and more empirical research is needed to identify the mechanism. Most CHS patients discover the symptomatic relief of hot showers on their own and use this method to control symptoms 1. In a case study from Texas, a 27-year-old male patient with CHS reported he found relief in hot showers but over time, he became refractory to the hot water and ended up having to visit the ED 105. A diagnosis of CHS is confirmed when all symptoms resolve for a long period of time (∼12 months) with the cessation of marijuana 15. Patients who stop using marijuana but continue to experience cyclic vomiting are more likely to have CVS. It is typical that CHS symptoms resolve in a matter of days once marijuana is stopped; in some case reports, symptoms resolved in hours.
What are the possible complications of cannabinoid hyperemesis syndrome?
They also experience episodes of vomiting that return every few weeks or months. Neither the psychological treatments nor the pharmacological treatments seem to be that effective,” he said. “There is evidence that if you send a message to the brain that competes with the message that’s causing the nausea, vomiting, that you can suppress it,” Camilleri said. One possible explanation for this is called “gate control theory,” which postulates that to some extent, the brain can regulate how much pain it perceives. Doctors at the hospital ran tests and ordered scans but could not name the source of her unrelenting nausea and vomiting.
Living With Cannabinoid Hyperemesis Syndrome
- Gastric motility and gastroparesis must be discussed in the context of CHS.
- Cannabis concentrates, made from leftover leaves and other waste products from the plant, are sold to “dab” onto cannabis for smoking; these dabbed-on cannabis extracts may contain 10 times the pesticides of the buds 67, 69, 70.
- However, researchers have yet to determine the cause of CHS since it does not affect all users of marijuana.
- Seventy percent of pa tients reported symptoms typically began in the morning 120.
Per the Nelson Textbook of Pediatrics, cyclic vomiting syndrome is defined by having sudden onset episodes of vomiting, having at least four bouts of vomiting per hour, and often having 12 to 15 episodes of vomiting per day. These episodes of vomiting are often separated by weeks or months, and there is a return to baseline between episodes. Importantly, for the definition of cyclic vomiting syndrome, these episodes of vomiting cannot be attributed to other disorders.
Supportive Care


Engaging resources such as social workers, addiction specialists, and other community and behavioral supports should be considered when making recommendations for cannabis cessation to patients with chronic cannabis use and suspected CHS. Certain risk factors for CHS, such as long-term cannabis use, can also contribute to the development of comorbidities like mental health issues and substance use disorders. CHS syndrome causes cyclic vomiting from chronic cannabis use and is not linked to multiple sclerosis or immune cell-related side effects.
Other pharmacologic alternatives were also explored with mixed to unproven efficacy. Corticosteroids, histamine-receptor antagonists, neurokinin-1 receptor antagonists, serotonin receptor antagonists, and opioids have been explored in case reports and preliminary studies but have not yet how long does it take to recover from cannabinoid hyperemesis syndrome adequately proven efficacy 42. If you already suspect you’re at risk, the best move is to cut back or quit cannabis altogether. Marijuana dependency can develop, making it hard to stop, even if you realize it’s hurting your life. This doesn’t mean everyone who tries cannabis occasionally will wind up with this condition. Since CHS is caused by chronic marijuana use, the first and most critical step is stopping any cannabis product.


This rise may, in part, be due to recognition bias, as emergency department (ED) physicians fail to recognize cyclic vomiting in more than 80% of cases 14. Both conditions predominantly affect younger individuals, with CHS showing a higher prevalence in males, which aligns with the higher rates of cannabis use among men. While CVS tends to be more common in women according to some studies, gender biases in both conditions remain inconclusive 15. Studies exploring novel treatments, diagnostic criteria, or the pathophysiology of CHS were also prioritized. People with CHS also tend to have a strong urge to take very hot showers or baths. That’s because hot water can help ease cannabinoid hyperemesis syndrome symptoms like nausea.
Addiction Therapy FAQs
He consented to IV haloperidol 1 mg which relieved his symptoms and produced no adverse effects; he subsequently received two more IV doses of 2 mg before he was discharged 114. An 18-year-old patient diagnosed with CHS refused to stop using marijuana and was treated in-clinic with haloperidol followed by outpatient 5 mg haloperidol which relieved her symptoms of nausea and vomiting. The patient discontinued haloperidol on her own after 3 weeks and was subsequently lost to follow-up 113. In clinical practice CHS is most often confused with cyclic vomiting syndrome (CVS).
- This effect causes delayed gastric emptying and continues to inhibit transit through the small intestine.
- Therefore, there is a lack of recognition and knowledge of the syndrome by sufferers and physicians.
- Some researchers have published their findings from their personal experience with the condition in clinical journals.
- A 37-year-old man in profound distress suffering hyperemesis presents at the ED, stating he had similar experiences in the past which could be relieved with hot showers, but this time hot water provided no relief.
- In animal models, CB1 receptor activation in the dorsal vagal complex of the brainstem mediates this effect 35,36.
You begin to regain lost weight and find that hot showers are no longer necessary for comfort. Doctors have only identified cannabinoid hyperemesis syndrome in the recent past. That means a lot of research is still ongoing to figure out exactly why it happens. Current findings suggest that the body’s naturally stored cannabinoids might https://ecosoberhouse.com/ eventually overwhelm receptors in the gut or other systems, flipping the usual script where cannabis often helps with nausea. Cannabinoid hyperemesis syndrome (CHS) is a condition that you might get if you’ve regularly smoked weed or used marijuana in some other form for a long time. CHS causes you to have repeated episodes of vomiting, severe nausea, stomach pain, and dehydration.


People might need to skip work, school, or social activities because they’re too sick to function normally. Over time, the act of bathing or showering excessively can also lead to its own set of issues. Hot water helps calm the symptoms for a while, but the relief doesn’t last long after stepping out. The rise in cannabis legalization could also mean more people have ready access to stronger strains.